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Article

TERT Promoter Mutations Are Enriched in Oral Cavity Cancers and Associated With Locoregional Recurrence.

JCO precision oncology - 1 Aug 2021

Yu Yao, Fan Dan, Song Xinmao, Zakeri Kaveh, Chen Linda, Kang Jung, McBride Sean, Tsai C Jillian, Dunn Lara, Sherman Eric, Katabi Nora, Dogan Snjezana, Cracchiolo Jennifer, Cohen Marc, Boyle Jay O, Lee Mark, Valero Cristina, Wang Jingming, Wong Richard, Morris Luc, Riaz Nadeem, Lee Nancy

Abstract excerpt

Telomerase reverse transcriptase (TERT) promoter mutations are prognostic in many cancers and have been observed in human papillomavirus (HPV)-negative head and neck squamous cell carcinomas (HNSCCs). However, the role of TERT promoter mutations in HPV-negative HNSCCs remains poorly understood in these cancers, which have increased risk for locoregional failure (LRF). PATIENTS AND METHODS: We retrospectively...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 34381934
DOI: 10.1200/PO.20.00515
PMCID: PMC8345918

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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