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Article

TERT promoter mutations in head and neck squamous cell carcinoma: A systematic review and meta-analysis on prevalence and prognostic significance.

Oral oncology - 1 May 2023

Boscolo-Rizzo Paolo, Tirelli Giancarlo, Polesel Jerry, Sia Egidio, Phillips Veronica, Borsetto Daniele, De Rossi Anita, Giunco Silvia

Abstract excerpt

OBJECTIVES: To estimate the prevalence of two most common and mutually exclusive -124 C > T and -146 C > T TERT promoter mutations in HNSCC and analyse their prognostic role. MATERIALS AND METHODS: The databases Medline (via Ovid), Embase (via Ovid), Cochrane Library, Scopus, and Web of Science (Core Collection) were searched from inception to December 2022 to identify studies analysing TERT promoter mutations in...

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Identifiers

PMID: 37075587
DOI: 10.1016/j.oraloncology.2023.106398

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