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Article

Prevalence of promoter mutations in the TERT gene in oral cavity squamous cell carcinoma.

Head & neck - 1 Jun 2017

Chang Kai-Ping, Wang Chun-I, Pickering Curtis R, Huang Yenlin, Tsai Chi-Neu, Tsang Ngan-Ming, Kao Huang-Kai, Cheng Ming-Huei, Myers Jeffrey N

Abstract excerpt

BACKGROUND: Mutations in the human telomerase reverse transcriptase (TERT) promoter contribute to increased TERT activity. The purpose of the present study was to assess the prevalence of TERT promoter mutations in oral cavity squamous cell carcinoma (SCC). METHODS: Total DNA was extracted from 201 oral cavity SCC tumors and adjacent normal tissues. Primers were used to amplify the sequence region containing 2...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 28230921
DOI: 10.1002/hed.24728

Genes

TERT

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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