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Article

TERT Promoter Mutations Frequency Across Race, Sex, and Cancer Type.

The oncologist - 5 Jan 2024

El Zarif Talal, Machaalani Marc, Nawfal Rashad, Nassar Amin H, Xie Wanling, Choueiri Toni K, Pomerantz Mark

Abstract excerpt

BACKGROUND: Telomerase reverse transcriptase (TERT) gene promoter mutations have been explored, as biomarkers of improved survival for patients with cancer receiving immune checkpoint inhibitors. We sought to investigate their prevalence by race and sex across different cancer types to inform patient selection in clinical trials. RESULTS: In this observational study, 31 925 patients with cancer underwent...

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Share to TERT gene
Share to Head and Neck Neoplasms
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Promoter Regions, Genetic

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Share to Telomeres, Telomerase, and Senescence

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Source

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Identifiers

PMID: 37462445
DOI: 10.1093/oncolo/oyad208
PMCID: PMC10769781

Genes

TERT

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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