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Article

Resistin deletion protects against heart failure injury by targeting DNA damage response

28 Jul 2021

Abstract excerpt

AIMS: Increased resistin (Retn) levels are associated with development of cardiovascular diseases. However, the role of Retn in heart failure (HF) is still unclear. Here we probed the functional and molecular mechanism underlying the beneficial effect of Retn deletion in HF. METHODS AND RESULTS: Wild-type (WT) and adipose tissue-specific Retn-knockout (RKO) mice were subjected to transverse aortic constriction...

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PMID: 34324657
DOI: 10.1093/cvr/cvab234

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