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CD163⁺/Dab2⁺ Macrophages Alleviate Cardiac Hypertrophy via Nrg2/ErbB4-Mediated Mitochondrial Reprogramming

2025-05-26

Abstract excerpt

<h4>ABSTRACT</h4> <h4>Background</h4> Pathological cardiac hypertrophy is a hallmark of numerous cardiovascular diseases, yet effective targeted therapies remain elusive in current clinical practice. Cardiac macrophages contribute to disease progression, but the underlying mechanisms have not been fully elucidated. <h4>Methods</h4> Single-nucleus RNA-sequencing, bulk RNA-sequencing, proteomics, metabolomics, an...

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Literature Corpus work: ec643d8f-87d0-532a-a2aa-077c559c2425
DOI: 10.1101/2025.05.22.655661

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