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Article

Sex-specific cardioprotective role of miR-30a-5p through estrogen-dependent mechanisms in a mouse model of heart failure.

Cardiovascular diabetology - 29 Jan 2026

Zhang Le, Quan Minxue, Zhang Xiao-Cheng, Zhang Shi-Yao, Chen Jia-Feng, Yu Li-Qing, Fu Guo, Li Gang, Wang Ruiying

Abstract excerpt

BACKGROUND: In recent years, except for the well-known heart failure with reduced ejection fraction (HFrEF), the incidence of heart failure with preserved ejection fraction (HFpEF) and heart failure with mildly reduced ejection fraction (HFmrEF) among the classification of heart failure (HF) has been increasing. However, due to their complex mechanisms, current research remains insufficient to address clinical...

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Source

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Identifiers

PMID: 41612389
DOI: 10.1186/s12933-026-03090-7
PMCID: PMC12857088

Genes

APOB
ITGAD
ITGAM
APOA1
ESRRA
FGA
FGB
PELP1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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