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Case Study 10: A Case to Investigate Acetyl Transferase Kinetics.

Methods in molecular biology (Clifton, N.J.) - 1 Jan 2021

Dumouchel Jennifer L, Kramlinger Valerie M

Abstract excerpt

Major routes of metabolism for marketed drugs are predominately driven by enzyme families such as cytochromes P450 and UDP-glucuronosyltransferases. Less studied conjugative enzymes, like N-acetyltransferases (NATs), are commonly associated with detoxification pathways. However, in the clinic, the high occurrence of NAT polymorphism that leads to slow and fast acetylator phenotypes in patient populations has been...

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PMID: 34272717
DOI: 10.1007/978-1-0716-1554-6_29

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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