Article
Pharmacogenetics, Regulation and Structural Properties of the Drugmetabolizing Enzymes Arylamine N-acetyltransferases.
2004-12-01
Abstract excerpt
Xenobiotic-metabolizing enzymes (XME) are responsible for the biotransformation of a vast range of compounds. Arylamine N-acetyltransferases (NAT) are XME responsible for the acetylation of many arylamine and heterocyclic amines. They therefore, play an important role in the detoxification and activation of numerous drugs and carcinogens. Two closely related isoforms (NAT1 and NAT2) have been described in humans....
Topics
Open a Topic to create a Post that cites this publication.
Identifiers and source
- Literature Corpus work
- 62eb17e3-5be8-5499-a443-a99a857ac3b1
- DOI
- 10.2174/1570160043377286