Article
Neurostructural correlates of BDNF rs6265 genotype in youth bipolar disorder.
Bipolar disorders - 1 Mar 2022
Kennedy Kody G, Shahatit Zaid, Dimick Mikaela K, Fiksenbaum Lisa, Freeman Natalie, Zai Clement C, Kennedy James L, MacIntosh Bradley J, Goldstein Benjamin I
Abstract excerpt
OBJECTIVE: Brain-derived neurotrophic factor (BDNF) rs6265 single-nucleotide polymorphism has been associated with bipolar disorder (BD), and with brain structure among adults with BD. We set out to investigate the association of the BDNF rs6265 Met allele with neurostructural phenotypes in youth BD. METHODS: Caucasian youth (N = 99; 13-20 years; n = 56 BD, n = 43 age and sex-matched healthy controls) underwent...
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