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Article

Antioxidative Defense Genes and Brain Structure in Youth Bipolar Disorder.

The international journal of neuropsychopharmacology - 11 Feb 2022

Zou Yi, Kennedy Kody G, Grigorian Anahit, Fiksenbaum Lisa, Freeman Natalie, Zai Clement C, Kennedy James L, MacIntosh Bradley J, Goldstein Benjamin I

Abstract excerpt

BACKGROUND: Oxidative stress is implicated in the neuropathology of bipolar disorder (BD). We investigated the association of single-nucleotide polymorphisms (SNPs) in the antioxidative genes superoxide dismutase 2 (SOD2) and glutathione peroxidase 3 (GPX3) with structural neuroimaging phenotypes in youth BD. METHODS: SOD2 rs4880 and GPX3 rs3792797 SNP genotypes, along with structural magnetic resonance imaging,...

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Identifiers

PMID: 34387669
DOI: 10.1093/ijnp/pyab056
PMCID: PMC8832218

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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