Neurostructural phenotypes of CACNA1C rs1006737 in adolescents with bipolar disorder and healthy controls.

doi:10.1016/j.pnpbp.2020.110071

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Article

Neurostructural phenotypes of CACNA1C rs1006737 in adolescents with bipolar disorder and healthy controls.

Progress in neuro-psychopharmacology & biological psychiatry - 10 Jan 2021

Shonibare Daniel O, Patel Ronak R, Islam Alvi H, Metcalfe Arron W S, Fiksenbaum Lisa, Freeman Natalie, MacIntosh Bradley J, Kennedy James L, Goldstein Benjamin I

Abstract excerpt

OBJECTIVE: Investigate the effects of CACNA1C rs1006737 on cortical and subcortical neurostructural phenotypes in Caucasian bipolar disorder (BD) and healthy control (HC) adolescents. METHODS: Seventy-one adolescents (14-20 years; 38BD, 33HC) underwent 3-Tesla Magnetic Resonance Imaging (MRI). Region of interest (ROI) and vertex-wise analyses examined cortical volume, surface area (SA), and thickness, as well as...

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PMID: 32800865
DOI: 10.1016/j.pnpbp.2020.110071

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