Reduced hippocampus volume and memory performance in bipolar disorder patients carrying the BDNF val66met met allele.

doi:10.1016/j.jad.2016.03.044

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Article

Reduced hippocampus volume and memory performance in bipolar disorder patients carrying the BDNF val66met met allele.

Journal of affective disorders - 1 Jul 2016

Cao Bo, Bauer Isabelle E, Sharma Ajaykumar N, Mwangi Benson, Frazier Thomas, Lavagnino Luca, Zunta-Soares Giovana B, Walss-Bass Consuelo, Glahn David C, Kapczinski Flavio, Nielsen David A, Soares Jair C

Abstract excerpt

BACKGROUND: Previous studies investigated the impact of brain-derived neurotrophic factor (BDNF) val66met (rs6265) on hippocampus volumes and neurocognition in bipolar disorders (BD), but the results were not consistent. This study aimed to investigate the effect of BDNF polymorphism on hippocampus volumes and memory performance in well-characterized adult populations diagnosed with type I BD (BD-I) and major...

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PMID: 27018938
DOI: 10.1016/j.jad.2016.03.044
PMCID: PMC5214589

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BDNF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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