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Article

Evidence of associations between bipolar disorder and the brain-derived neurotrophic factor (BDNF) gene.

Bipolar disorders - 1 Jan 2000

Sears Catherine, Markie David, Olds Robin, Fitches Alison

Abstract excerpt

OBJECTIVE: Brain-derived neurotrophic factor (BDNF) has important roles in neural cell growth and differentiation. Despite multiple lines of evidence suggesting BDNF as a possible contributor to the pathogenesis of bipolar disorder (BD), the results of genetic association studies have been mixed. We hypothesize that BDNF gene polymorphisms may confer increased susceptibility to BD. METHODS: Using a cohort of...

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Source

Identifiers

PMID: 22085476
DOI: 10.1111/j.1399-5618.2011.00955.x

Genes

BDNF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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