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Article

Genomic analyses of new genes and their phenotypic effects reveal rapid evolution of essential functions in Drosophila development.

PLoS genetics - 1 Jul 2021

Xia Shengqian, VanKuren Nicholas W, Chen Chunyan, Zhang Li, Kemkemer Clause, Shao Yi, Jia Hangxing, Lee UnJin, Advani Alexander S, Gschwend Andrea, Vibranovski Maria D, Chen Sidi, Zhang Yong E, Long Manyuan

Abstract excerpt

It is a conventionally held dogma that the genetic basis underlying development is conserved in a long evolutionary time scale. Ample experiments based on mutational, biochemical, functional, and complementary knockdown/knockout approaches have revealed the unexpectedly important role of recently evolved new genes in the development of Drosophila. The recent progress in the genome-wide experimental testing of...

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Identifiers

PMID: 34242211
DOI: 10.1371/journal.pgen.1009654
PMCID: PMC8270118

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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