Article
A P-element insertion screen identified mutations in 455 novel essential genes in Drosophila.
Genetics - 1 Jan 2003
Oh Su-Wan, Kingsley Tracy, Shin Hyun-hee, Zheng Zhiyu, Chen Hua-Wei, Chen Xiu, Wang Hong, Ruan Peizheng, Moody Michelle, Hou Steven X
Abstract excerpt
With the completion of the nucleotide sequences of several complex eukaryotic genomes, tens of thousands of genes have been predicted. However, this information has to be correlated with the functions of those genes to enhance our understanding of biology and to improve human health care. The Drosophila transposon P-element-induced mutations are very useful for directly connecting gene products to their...
Topics
- Animals
- DNA Transposable Elements
- Drosophila
- Genes, Lethal
- Mutation