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Article

Clinical prognostic value of different NPM1 mutations in acute myeloid leukemia patients.

Annals of hematology - 1 Jul 2024

Shi Yu, Chen Xiao, Jin Huimin, Zhu Liying, Hong Ming, Zhu Yu, Wu Yujie, Qiu Hairong, Wang Yan, Sun Qian, Jin Hui, Li Jianyong, Qian Sixuan, Qiao Chun

Abstract excerpt

BACKGROUND: Acute myeloid leukemia (AML) patients with various nucleophosmin 1 (NPM1) mutations are controversial in the prognosis. This study aimed to investigate the prognosis of patients according to types of NPM1 mutations (NPM1mut). METHODS: Bone marrow samples of 528 patients newly diagnosed with AML, were collected for morphology, immunology, cytogenetics, and molecular biology examinations. Gene mutations...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 38722387
DOI: 10.1007/s00277-024-05786-w

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