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[Association of Next Generation Sequencing Based Genotypic Profiling with MICM Characteristics in NPM1 Mutated Acute Myeloid Leukemia].

Zhongguo shi yan xue ye xue za zhi - 1 Feb 2022

Wang Biao, Ling Yun, Dai Li, Gu Wei-Ying, Zhang Xiu-Wen, Xing Shan-Shan, Li Hai-Qian

Abstract excerpt

OBJECTIVE: To explain the clinicobiological heterogeneity of NPM1 mutated (NPM1mut) acute myeloid leukemia (AML) by analyzing the association between next-generation sequencing (NGS) profiles and MICM characteristics in patients with this AML subtype. METHODS: Data of 238 NPM1mut patients with available NGS information on 112 genes related to blood disease was collected, and χ2 test and nonparametric test were...

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PMID: 35123604
DOI: 10.19746/j.cnki.issn.1009-2137.2022.01.010

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