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Article

Phenotypical modifications of immune cells are enhanced by extracellular matrix.

Experimental cell research - 15 Aug 2021

Teplický Tibor, Mateašík Anton, Balázsiová Zuzana, Kajo Karol, Vallová Miroslava, Filová Barbora, Trnka Michal, Čunderlíková Beata

Abstract excerpt

Immune cells not only constitute tumour microenvironment but they may even affect disease prognosis as a result of dual functional roles that they may play in tumour tissues. Two frequently used established immune cell lines (lymphocytic Jurkat and monocytic THP-1) were used to test whether microenvironmental factors, especially molecular components of extracellular matrix, can shape the phenotype of immune...

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Identifiers

PMID: 34174319
DOI: 10.1016/j.yexcr.2021.112710

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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