Article
The Impact of the Cancer Microenvironment on Macrophage Phenotypes.
Frontiers in immunology - 1 Jan 2020
Ham Sunyoung, Lima Luize G, Lek Erica, Möller Andreas
Abstract excerpt
Within the tumor microenvironment, there is an intricate communication happening between tumor and stromal cells. This information exchange, in the form of cytokines, growth factors, extracellular vesicles, danger molecules, cell debris, and other factors, is capable of modulating the function of immune cells. The triggering of specific responses, including phenotypic alterations, can ultimately result in either...
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