Article
Interleukin-1 induces major phenotypic changes in human skin microvascular endothelial cells.
Journal of cellular physiology - 1 Oct 1997
Romero L I, Zhang D N, Herron G S, Karasek M A
Abstract excerpt
To determine the role of the pleiotropic cytokine interleukin-1 (IL-1) on the activation of endothelial cells during inflammation and angiogenesis, pure populations of human dermal microvascular endothelial cells (HDMEC) were obtained by immunoaffinity purification using Ulex europaeus agglutinin-1 and platelet endothelial cell adhesion molecule-1 (PECAM-1) antibody. Exposure of HDMEC to IL-1beta induced...
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