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Article

Culture supernatants of different colon cancer cell lines induce specific phenotype switching and functional alteration of THP-1 cells.

Cellular immunology - 1 Jul 2014

Wu Tsung-Han, Li Ying-Ying, Wu Tai-Ling, Chang John W-C, Chou Wen-Chi, Hsieh Ling-Ling, Chen Jim-Ray, Yeh Kun-Yun

Abstract excerpt

We developed an in vitro model to evaluate the effect of products secreted from different colorectal cancer (CRC) cell lines on specific phenotypic switching and functional alterations in THP-1 cells. We co-cultured the human monocytic cell line, THP-1, or phorbol-12-myristate-13-acetate (PMA)-tr...

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Identifiers

PMID: 24960291
DOI: 10.1016/j.cellimm.2014.05.015

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-24960291-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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