Phenotypic changes in lipopolysaccharide-treated cloned cells derived from transplantable rat malignant fibrous histiocytoma.

doi:10.1292/jvms.58.10_1017

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Article

Phenotypic changes in lipopolysaccharide-treated cloned cells derived from transplantable rat malignant fibrous histiocytoma.

The Journal of veterinary medical science - 1 Oct 1996

Yamate J, Tajima M, Shibuya K, Kuwamura M, Kotani T, Sakuma S

Abstract excerpt

To investigate a possible phenotypic modulation, MT-8L and MT-9L cells were induced by in vitro culture of undifferentiated MT-8 and fibrohistiocytic MT-9 cells, which had been established from a rat malignant fibrous histiocytoma (MFH), in the medium containing 10 micrograms lipopolysaccharide (LPS)/ml. MT-8L and MT-9L gave greater positive reactions for histiocytic lysosomal markers and showed ultrastructures...

Topics

Animals
Culture Media
Histiocytoma, Benign Fibrous
Lipopolysaccharides
Male
Neoplasm Transplantation
Phenotype
Rats
Rats, Inbred F344
Tumor Cells, Cultured

Source

Open in PubMed

Identifiers

PMID: 8916004
DOI: 10.1292/jvms.58.10_1017

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