Article
In vitro analysis of HIV- and non-HIV-infected monocytes/macrophages from healthy subjects and patients with malignant tumours.
Research in virology - 1 Jan 2000
Müller H, Schuster K, Krüger S, Glienke W, Rübsamen-Waigmann H, Stutte H J
Abstract excerpt
Phenotype and release of IL1 alpha, IL6 and TNF alpha were examined in monocytes derived from 14 healthy donors and 24 tumour patients in a long-term culture using immunohistochemical, RNA in situ hybridization and ELISA techniques. After stimulation with LPS and IFN-gamma, blood monocytes and resulting macrophages showed an overall decrease in cytokine release from the 6th to the 48th day of culture, both with...
Topics
- Antigens, Differentiation
- HIV Infections
- Hodgkin Disease
- Humans
- Immunohistochemistry
- In Situ Hybridization
- In Vitro Techniques
- Interferon-gamma
- Interleukin-1
- Interleukin-6
- Lipopolysaccharides