Inflammasome genes polymorphisms may influence the development of hepatitis C in the Amazonas, Brazil.

doi:10.1371/journal.pone.0253470

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Article

Inflammasome genes polymorphisms may influence the development of hepatitis C in the Amazonas, Brazil.

PloS one - 1 Jan 2021

Toro Diana Mota, Ramasawmy Rajendranath, Silva Neto Pedro Vieira, Pereira Grenda Leite, Sarmento Priscila Santos, Dray Hanna Lara Silva Negreiros, Sousa Keyla Santos, Affonso Juliana Santos, Silva Jéssica Albuquerque, Garcia Nadja Pinto, Barbieri Marilú Victória, Victória Flamir Silva, Donadi Eduardo Antônio, Costa Allyson Guimarães, Ogusku Mauricio Morishi, Sadahiro Aya, Tarragô Andréa Monteiro, Malheiro Adriana

Abstract excerpt

Hepatitis C is considered a major public health problem caused by the hepatitis C virus (HCV). Viral infections are known to induce production of IL1β through the signaling pathway of inflammasomes. Emerging evidences suggest that Inflammasome genes may influence the immune response against HCV as the host genetic background may contribute to the balance between acute and chronic inflammation. We investigated in...

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PMID: 34161370
DOI: 10.1371/journal.pone.0253470
PMCID: PMC8221483

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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