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Article

Interferon-related genetic markers of necroinflammatory activity in chronic hepatitis C.

PloS one - 1 Jan 2017

López-Rodríguez Rosario, Hernández-Bartolomé Ángel, Borque María Jesús, Rodríguez-Muñoz Yolanda, Martín-Vílchez Samuel, García-Buey Luisa, González-Moreno Leticia, Real-Martínez Yolanda, Muñoz de Rueda Paloma, Salmerón Javier, Vidal-Castiñeira José Ramón, López-Larrea Carlos, Rodrigo Luis, Moreno-Otero Ricardo, Sanz-Cameno Paloma

Abstract excerpt

INTRODUCTION: Chronic hepatitis C (CHC) is a major cause of liver disease worldwide which often leads to progressive liver inflammation, fibrosis, cirrhosis and hepatocellular carcinoma (HCC). CHC displays heterogeneous progression depending on a broad set of factors, some of them intrinsic to each individual such as the patient's genetic profile. This study aims to evaluate the contribution of certain genetic...

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Identifiers

PMID: 28704535
DOI: 10.1371/journal.pone.0180927
PMCID: PMC5507534

Genes

RNASEL
TYK2
OAS1
IFNAR1
JAK1
SOCS1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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