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Article

Polimorphisms in inflammasome genes are involved in the predisposition to systemic lupus erythematosus.

Autoimmunity - 1 Jun 2012

Pontillo Alessandra, Girardelli Martina, Kamada Anselmo J, Pancotto Joao A T, Donadi Eduardo A, Crovella Sergio, Sandrin-Garcia Paula

Abstract excerpt

Recent findings provide evidence of inflammasome critical role in the predisposition to autoimmune disorders. The involvement of inflammasome in the pathogenesis of systemic lupus erythematosus (SLE) has been hypothesized even if no significant association within inflammasome genes mutations or polymorphisms and lupus has been reported yet. We analyzed 14 single nucleotide polymorphisms (SNPs) within 7...

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Source

Identifiers

PMID: 22235789
DOI: 10.3109/08916934.2011.637532

Genes

NLRP1
AIM2
CARD8
CASP1
NLRC4
NLRP3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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