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Article

Polymorphisms in inflammasome genes and risk of coal workers' pneumoconiosis in a Chinese population.

PloS one - 1 Jan 2012

Ji Xiaoming, Hou Zhiguo, Wang Ting, Jin Kexin, Fan Jingjing, Luo Chen, Chen Minjuan, Han Ruhui, Ni Chunhui

Abstract excerpt

BACKGROUND: Coal workers' pneumoconiosis (CWP), resulting from the inhalation of silica-containing coal mine dust, is characterized by fibrosing nodular lesions that eventually develop into progressive pulmonary fibrosis. Recently, it has been hypothesized that inflammasomes could have a crucial role in the host response to silica and recent studies show that the inflammasome contributes to inflammation and...

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Source

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Identifiers

PMID: 23110140
DOI: 10.1371/journal.pone.0047949
PMCID: PMC3478280

Genes

NLRP3
CARD8

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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