Polymorphisms and expression of inflammasome genes are associated with the development and severity of rheumatoid arthritis in Brazilian patients.

doi:10.1007/s00011-017-1119-2

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Article

Polymorphisms and expression of inflammasome genes are associated with the development and severity of rheumatoid arthritis in Brazilian patients.

Inflammation research : official journal of the European Histamine Research Society ... [et al.] - 1 Mar 2018

Addobbati Catarina, da Cruz Heidi Lacerda Alves, Adelino José Eduardo, Melo Tavares Ramos Amanda Luíze, Fragoso Thiago Sotero, Domingues Alexandre, Branco Pinto Duarte Ângela Luiza, Oliveira Renê Donizeti Ribeiro, Louzada-Júnior Paulo, Donadi Eduardo Antônio, Pontillo Alessandra, de Azevêdo Silva Jaqueline, Crovella Sergio, Sandrin-Garcia Paula

Abstract excerpt

OBJECTIVE: In the present study, we analyzed the possible association of inflammasome gene variants and expression to rheumatoid arthritis (RA)'s development and severity in the Brazilian population. MATERIALS AND METHODS: Thirteen single nucleotide polymorphisms within six inflammasome genes (NLRP1, NLRP3, NLRC4, AIM2, CARD8, CASP1) as well as IL1B and IL18 genes in two different Brazilian populations (from...

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Identifiers

PMID: 29230505
DOI: 10.1007/s00011-017-1119-2

Genes

NLRP3
CARD8
CASP1
NLRC4
AIM2
NLRP1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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