Article

Systematic comparative benchmarking of computational methods for the detection of transposable elements in long-read sequencing data

2025-09-30

Abstract excerpt

<h4>Background</h4> Mobile element insertions, particularly transposable elements (TEs) such as Alu, LINE-1 (L1), SVA, and endogenous retroviruses (ERVs), represent a major source of human genetic variation and have been implicated in evolution, genomic instability, and disease. Although long-read sequencing generally outperforms short-read sequencing for the characterisation of such elements, their accurate dete...

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Literature Corpus work: e8a7b7cd-0b48-5872-8602-2b722308ed18
DOI: 10.1101/2025.09.29.679192

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