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Article

A high throughput screen for active human transposable elements.

BMC genomics - 1 Feb 2018

Kvikstad Erika M, Piazza Paolo, Taylor Jenny C, Lunter Gerton

Abstract excerpt

BACKGROUND: Transposable elements (TEs) are mobile genetic sequences that randomly propagate within their host's genome. This mobility has the potential to affect gene transcription and cause disease. However, TEs are technically challenging to identify, which complicates efforts to assess the impact of TE insertions on disease. Here we present a targeted sequencing protocol and computational pipeline to identify...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 29390960
DOI: 10.1186/s12864-018-4485-4
PMCID: PMC5796560

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