Article
[N-aсetyltransferase (NAT2) gene polymorphism and gene network analysis].
Biomeditsinskaia khimiia - 1 May 2021
Tiis R P, Osipova L P, Galieva E R, Lichman D V, Voronina E N, Melikhova A V, Orlov Y L, Filipenko M L
Abstract excerpt
To search for new targets of therapy, it is necessary to reconstruct the gene network of the disease, and identify the interaction of genes, proteins, and drug compounds. Using the online bioinformatics tools we have analyzed the current data set related to the metabolism of xenobiotics, mediated by the N-acetyltransferase 2 (NAT2) gene. The study of allelic polymorphism of the NAT2 gene has a prognostic value,...
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