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Article

NAT2 global landscape: Genetic diversity and acetylation statuses from a systematic review.

PloS one - 1 Jan 2023

Gutiérrez-Virgen Jorge E, Piña-Pozas Maricela, Hernández-Tobías Esther A, Taja-Chayeb Lucia, López-González Ma de Lourdes, Meraz-Ríos Marco A, Gómez Rocío

Abstract excerpt

Arylamine N-acetyltransferase 2 has been related to drug side effects and cancer susceptibility; its protein structure and acetylation capacity results from the polymorphism's arrays on the NAT2 gene. Absorption, distribution, metabolism, and excretion, cornerstones of the pharmacological effects, have shown diversity patterns across populations, ethnic groups, and even interethnic variation. Although the 1000...

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Identifiers

PMID: 37023111
DOI: 10.1371/journal.pone.0283726
PMCID: PMC10079069

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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