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Article

Following Transplantation for Acute Myelogenous Leukemia, Donor KIR Cen B02 Better Protects against Relapse than KIR Cen B01.

Journal of immunology (Baltimore, Md. : 1950) - 15 Jun 2021

Guethlein Lisbeth A, Beyzaie Niassan, Nemat-Gorgani Neda, Wang Tao, Ramesh Vidhyalakshmi, Marin Wesley M, Hollenbach Jill A, Schetelig Johannes, Spellman Stephen R, Marsh Steven G E, Cooley Sarah, Weisdorf Daniel J, Norman Paul J, Miller Jeffrey S, Parham Peter

Abstract excerpt

In the treatment of acute myelogenous leukemia with allogeneic hematopoietic cell transplantation, we previously demonstrated that there is a greater protection from relapse of leukemia when the hematopoietic cell transplantation donor has either the Cen B/B KIR genotype or a genotype having two or more KIR B gene segments. In those earlier analyses, KIR genotyping could only be assessed at the low resolution of...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Leukemia, Myeloid, Acute

Share to Receptors, KIR

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Identifiers

PMID: 34117109
DOI: 10.4049/jimmunol.2100119
PMCID: PMC8664929

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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