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Article

Donor selection for natural killer cell receptor genes leads to superior survival after unrelated transplantation for acute myelogenous leukemia.

Blood - 7 Oct 2010

Cooley Sarah, Weisdorf Daniel J, Guethlein Lisbeth A, Klein John P, Wang Tao, Le Chap T, Marsh Steven G E, Geraghty Daniel, Spellman Stephen, Haagenson Michael D, Ladner Martha, Trachtenberg Elizabeth, Parham Peter, Miller Jeffrey S

Abstract excerpt

Killer-cell immunoglobulin-like receptor (KIR) genes form a diverse, immunogenetic system. Group A and B KIR haplotypes have distinctive centromeric (Cen) and telomeric (Tel) gene-content motifs. Aiming to develop a donor selection strategy to improve transplant outcome, we compared the contribution of these motifs to the clinical benefit conferred by B haplotype donors. We KIR genotyped donors from 1409...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Hematopoietic Stem Cell Transplantation

Share to Killer Cells, Natural

Share to Leukemia, Myeloid, Acute

Share to Precursor Cell Lymphoblastic Leukemia-Lymphoma

Share to Receptors, KIR

Source

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Identifiers

PMID: 20581313
DOI: 10.1182/blood-2010-05-283051
PMCID: PMC2953880

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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