Integrating killer cell immunoglobulin-like receptor highresolution genotyping for predicting transplant outcomes in allogeneic hematopoietic stem cell transplantation.

doi:10.3324/haematol.2024.287061

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Integrating killer cell immunoglobulin-like receptor highresolution genotyping for predicting transplant outcomes in allogeneic hematopoietic stem cell transplantation.

Haematologica - 1 Mar 2026

Schäfer Antonia, Buhler Stéphane, Farias Ticiana D J, Kichula Katherine M, Baldomero Helen, Sollet Zuleika Calderin, Ferrari-Lacraz Sylvie, Micheli Baptiste, Masouridi-Levrat Stavroula, Mesquita Vanessa, Kürsteiner Oliver, Nair Gayathri, Halter Jörg, Güngör Tayfun, Schneidawind Dominik, Chalandon Yves, Passweg Jakob R, Norman Paul J, Villard Jean

Abstract excerpt

The success of hematopoietic stem cell transplantation (HSCT) partly relies on the beneficial graft-versus-leukemia effect, mediated by alloreactive natural killer cells through their killer cell immunoglobulin-like receptors (KIR). Conflicting results have been reported regarding the impact of the KIR immunogenetic system on HSCT outcomes with a scarcity of data interrogating the effect of KIR allelic...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 40637775
DOI: 10.3324/haematol.2024.287061
PMCID: PMC12951152

Genes

C2
KIR2DL2
KIR2DL3
KIR3DL1

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