Article
Influence of donor KIR genotypes on reduced relapse risk in acute myelogenous leukemia after hematopoietic stem cell transplantation in patients with CMV reactivation.
Leukemia research - 1 Dec 2019
Nakamura Ryotaro, Gendzekhadze Ketevan, Palmer Joycelynne, Tsai Ni-Chun, Mokhtari Sally, Forman Stephen J, Zaia John A, Senitzer David, Marcucci Guido, Stein Anthony
Abstract excerpt
Multiple retrospective studies have demonstrated an association between cytomegalovirus (CMV) reactivation and reduced risk of AML relapse. However, the potential mechanism explaining this association remains elusive. We investigated a homogeneous cohort of 288 adult patients with AML in remission who received allogeneic hematopoietic stem cell transplantation (HCT) from matched sibling/unrelated donors between...
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