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Article

TP53 Targeted Deep Sequencing of Cell-Free DNA in Esophageal Squamous Cell Carcinoma Using Low-Quality Serum: Concordance with Tumor Mutation.

International journal of molecular sciences - 26 May 2021

Nasrollahzadeh Dariush, Roshandel Gholamreza, Delhomme Tiffany Myriam, Avogbe Patrice Hodonou, Foll Matthieu, Saidi Farrokh, Poustchi Hossein, Sotoudeh Masoud, Malekzadeh Reza, Brennan Paul, Mckay James, Hainaut Pierre, Abedi-Ardekani Behnoush

Abstract excerpt

Circulating cell-free DNA (cfDNA) is emerging as a potential tumor biomarker. CfDNA-based biomarkers may be applicable in tumors without an available non-invasive screening method among at-risk populations. Esophageal squamous cell carcinoma (ESCC) and residents of the Asian cancer belt are examples of those malignancies and populations. Previous epidemiological studies using cfDNA have pointed to the need for...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 34073316
DOI: 10.3390/ijms22115627
PMCID: PMC8197963

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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