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Applications for Circulating Cell-Free DNA in Oral Squamous Cell Carcinoma: A Non-Invasive Approach for Detecting Structural Variants, Fusions, and Oncoviruses

2023-11-30

Abstract excerpt

Circulating cell-free DNA (cfDNA) has been widely used as a prognostic marker for different cancers. In this study, we used 30 cfDNA samples from oral squamous cell carcinoma (OSCC), 199 public OSCC and 192 normal samples to study various correlation factors that could improve the early-stage diagnostics and/or prognosis of OSCC. We found that OSCC patient cfDNA concentration can serve as an indicator of tumor sta...

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Literature Corpus work: 117ecbe1-ffa2-510f-84c5-6f54f5f669ab
DOI: 10.1101/2023.11.29.23299177

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