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Article

Targeted Next-Generation Sequencing of Plasma Cell-Free DNA in Korean Patients with Hepatocellular Carcinoma.

Annals of laboratory medicine - 1 Mar 2021

Chae Hyojin, Sung Pil Soo, Choi Hayoung, Kwon Ahlm, Kang Dain, Kim Yonggoo, Kim Myungshin, Yoon Seung Kew

Abstract excerpt

BACKGROUND: Hepatocellular carcinoma (HCC) is the second-most-common cause of cancer-related deaths worldwide, and an accurate and non-invasive biomarker for the early detection and monitoring of HCC is required. We assessed pathogenic variants of HCC driver genes in cell-free DNA (cfDNA) from HCC patients who had not undergone systemic therapy. METHODS: Plasma cfDNA was collected from 20 HCC patients, and deep...

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Identifiers

PMID: 33063681
DOI: 10.3343/alm.2021.41.2.198
PMCID: PMC7591296

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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