Article

Multiregion sequencing reveals the genetic correlation of esophageal squamous cell carcinoma and matched cell-free DNA

2020-09-15

Abstract excerpt

<title>Abstract</title> <p><bold>Background</bold>: The aim of this study was to assess whether both ubiquitous and heterogeneous somatic mutations could be detected in circulating cell-free DNA (cfDNA) from patients with esophageal squamous cell carcinoma (ESCC). <bold>Methods</bold>: Paired multi-regional tumor tissues, cfDNA and white blood cells (WBCs) collected from five ESCC patients before treatment from a...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 1d419682-87e1-5f7b-a749-c93e737bf2e8
DOI: 10.21203/rs.3.rs-74129/v1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Multiregion sequencing reveals the genetic correlation of esophageal squamous cell carcinoma and matched cell-free DNADOI 10.21203/rs.3.rs-74129/v1Read

Multi-region sequencing reveals genetic correlation between esophageal squamous cell carcinoma and matched cell-free DNA.Semantic proximity Read

Detection of somatic mutations in circulating cell-free DNA from patients with esophageal squamous cell carcinomaSemantic proximity Read

Comparative genomic analysis of esophageal squamous cell carcinoma among different geographic regionsSemantic proximity Read

TP53 Targeted Deep Sequencing of Cell-Free DNA in Esophageal Squamous Cell Carcinoma Using Low-Quality Serum: Concordance with Tumor Mutation.Semantic proximity Read

Cross-talk between next generation sequencing methodologies to identify genomic signatures of esophageal cancer.Semantic proximity Read

Somatic mutations of esophageal adenocarcinoma: a comparison between Black and White patientsSemantic proximity Read

Whole-Exome Sequencing of Esophageal Submucosal Gland Duct AdenocarcinomaSemantic proximity Read

Genome-wide and panel-based cell-free DNA characterization of patients with resectable esophageal adenocarcinoma.Semantic proximity Read

Noninvasive diagnosis and monitoring of mutations by deep sequencing of circulating tumor DNA in esophageal squamous cell carcinoma.Semantic proximity Read

Whole exome sequencing of cell-free DNA - A systematic review and Bayesian individual patient data meta-analysis.Semantic proximity Read

Finding new cancer epigenetic and genetic biomarkers from cell-free DNA by combining SALP-seq and machine learning: esophageal cancer as an exampleSemantic proximity Read

Somatic mutations of esophageal adenocarcinoma: a comparison between Black and White patients.Semantic proximity Read