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Article

NGS-based mtDNA Profiling Could Reveal Genetic Alterations in Schizophrenia.

Current topics in medicinal chemistry - 1 Jan 2021

Ivanova Elena Mihailova, Kandilarova Snezhina Mihailova, Lukanov Tzvetelin Ivanov, Naumova Elissaveta Jordanova, Akabalieva Katerina Valentinova, Milanova Vihra Krumova

Abstract excerpt

BACKGROUND: Schizophrenia is a complex disease with a putative genetic background. It was hypothesized that impaired mitochondrial function due to genetic alterations in mitochondrial DNA (mtDNA) could contribute to neurological conditions, including mental disorders. The aim of the study was to find out possible pathogenic mutations and/or variants in mtDNA potentially related to schizophrenia development....

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Identifiers

PMID: 34060999
DOI: 10.2174/1568026621666210521155500

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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