Article
Systematic association studies of mitochondrial DNA variations in schizophrenia: focus on the ND5 gene.
Schizophrenia bulletin - 1 May 2008
Bamne Mikhil N, Talkowski Michael E, Moraes Carlos T, Manuck Stephen B, Ferrell Robert E, Chowdari Kodavali V, Nimgaonkar Vishwajit L
Abstract excerpt
Postmortem studies, as well as genetic association studies, have implicated mitochondrial dysfunction in schizophrenia (SZ). We conducted multistaged analysis to assess the involvement of mitochondrial DNA (mtDNA) variations in SZ. Initially, the entire mtDNA genome was sequenced in pools of DNA...
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