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Article

Examining the role of common and rare mitochondrial variants in schizophrenia.

PloS one - 1 Jan 2018

Gonçalves Vanessa F, Giamberardino Stephanie N, Crowley James J, Vawter Marquis P, Saxena Richa, Bulik Cynthia M, Yilmaz Zeynep, Hultman Christina M, Sklar Pamela, Kennedy James L, Sullivan Patrick F, Knight Jo

Abstract excerpt

Oxidative phosphorylation within mitochondria is the main source of aerobic energy for neuronal functioning, and the key genes are located in mitochondrial DNA. Deficits in oxidative phosphorylation functioning have been reported for schizophrenia, but efforts in the identification of genetic markers within the mitochondrial DNA that predispose to schizophrenia have been limited. We genotyped a set of...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 29370225
DOI: 10.1371/journal.pone.0191153
PMCID: PMC5784966

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