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Article

Do nuclear-encoded core subunits of mitochondrial complex I confer genetic susceptibility to schizophrenia in Han Chinese populations?

Scientific reports - 8 Jun 2015

Li Xiao, Zhang Wen, Tang Jinsong, Tan Liwen, Luo Xiong-jian, Chen Xiaogang, Yao Yong-Gang

Abstract excerpt

Schizophrenia is one of the most prevalent psychiatric disorders with complex genetic etiology. Accumulating evidence suggests that energy metabolism and oxidative stress play important roles in the pathophysiology of schizophrenia. Dysfunction of mitochondrial respiratory chain and altered expression of complex I subunits were frequently reported in schizophrenia. To investigate whether nuclear-encoded core...

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Identifiers

PMID: 26053550
DOI: 10.1038/srep11076
PMCID: PMC4459149

Genes

PGC
NDUFS1
NDUFS2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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