Article
Mitochondrial DNA (mtDNA) variants in the European haplogroups HV, JT, and U do not have a major role in schizophrenia.
American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics - 1 Oct 2014
Torrell Helena, Salas Antonio, Abasolo Nerea, Morén Constanza, Garrabou Glòria, Valero Joaquín, Alonso Yolanda, Vilella Elisabet, Costas Javier, Martorell Lourdes
Abstract excerpt
It has been reported that certain genetic factors involved in schizophrenia could be located in the mitochondrial DNA (mtDNA). Therefore, we hypothesized that mtDNA mutations and/or variants would be present in schizophrenia patients and may be related to schizophrenia characteristics and mitochondrial function. This study was performed in three steps: (1) identification of pathogenic mutations and variants in 14...
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