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Article

Mitochondrial mutations in subjects with psychiatric disorders.

PloS one - 1 Jan 2015

Sequeira Adolfo, Rollins Brandi, Magnan Christophe, van Oven Mannis, Baldi Pierre, Myers Richard M, Barchas Jack D, Schatzberg Alan F, Watson Stanley J, Akil Huda, Bunney William E, Vawter Marquis P

Abstract excerpt

A considerable body of evidence supports the role of mitochondrial dysfunction in psychiatric disorders and mitochondrial DNA (mtDNA) mutations are known to alter brain energy metabolism, neurotransmission, and cause neurodegenerative disorders. Genetic studies focusing on common nuclear genome variants associated with these disorders have produced genome wide significant results but those studies have not...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 26011537
DOI: 10.1371/journal.pone.0127280
PMCID: PMC4444211

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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