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Mitochondrial genome variations and functional characterization in Han Chinese families with schizophrenia.

Schizophrenia research - 1 Mar 2016

Bi Rui, Tang Jinsong, Zhang Wen, Li Xiao, Chen Shi-Yi, Yu Dandan, Chen Xiaogang, Yao Yong-Gang

Abstract excerpt

The relationship between mitochondrial DNA (mtDNA) variants and schizophrenia has been strongly debated. To test whether mtDNA variants are involved in schizophrenia in Han Chinese patients, we sequenced the entire mitochondrial genomes of probands from 11 families with a family history and maternal inheritance pattern of schizophrenia. Besides the haplogroup-specific variants, we found 11 nonsynonymous private...

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PMID: 26822593
DOI: 10.1016/j.schres.2016.01.011

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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