Article
Genetic interaction network has a very limited impact on the evolutionary trajectories in continuous culture-grown populations of yeast.
BMC ecology and evolution - 26 May 2021
Klim Joanna, Zielenkiewicz Urszula, Skoneczny Marek, Skoneczna Adrianna, Kurlandzka Anna, Kaczanowski Szymon
Abstract excerpt
BACKGROUND: The impact of genetic interaction networks on evolution is a fundamental issue. Previous studies have demonstrated that the topology of the network is determined by the properties of the cellular machinery. Functionally related genes frequently interact with one another, and they establish modules, e.g., modules of protein complexes and biochemical pathways. In this study, we experimentally tested the...
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