Article
Multiple genomic changes associated with reorganization of gene regulation and adaptation in yeast.
Molecular biology and evolution - 1 Jul 2013
David Lior, Ben-Harosh Yossef, Stolovicki Elad, Moore Lindsay S, Nguyen Michelle, Tamse Raquel, Dean Jed, Mancera Eugenio, Steinmetz Lars M, Braun Erez
Abstract excerpt
Frequently during evolution, new phenotypes evolved due to novelty in gene regulation, such as that caused by genome rewiring. This has been demonstrated by comparing common regulatory sequences among species and by identifying single regulatory mutations that are associated with new phenotypes. However, while a single mutation changes a single element, gene regulation is accomplished by a regulatory network...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.